Circadian rhythm disruption could lead to tumour growth

Disrupting normal circadian rhythms promotes tumour growth and suppresses the effects of a tumour-fighting drug, according to a new study publishing April 30 in the open-access journal PLOS Biology

Circadian rhythm disruption could lead to tumour growthThe study was done by Yool Lee, Amita Sehgal, and colleagues at the University of Pennsylvania. The results provide mechanistic support for ‘chronotherapy,’ the delivery of cancer drugs timed to the endogenous circadian rhythm. Circadian rhythms regulate many aspects of physiology from the organismic to the subcellular levels. Disruption of circadian rhythms, whether through jet […]

Study finds: Exercise can shift human body clock depending on time when people work out

Exercise can shift the human body clock, with the direction and amount of this effect depending on the time of day or night in which people exercise

Study finds: Exercise can shift human body clock depending on time when people work outThat’s according to new research in published in The Journal of Physiology. These findings suggest exercise could counter the effects of jet lag, shift work, and other disruptions to the body’s internal clock (e.g. military deployments) helping individuals adjust to shifted schedules. The circadian ‘body’ clock is the 24 hour cycle that regulates many physiological […]