Breakthrough: Scientists attempt gene editing inside the human body, for the first time

If successful, the new technique could give a major boost to the fledgling field of gene therapy. Scientists have edited people’s genes before, altering cells in the lab that are then returned to patients. There also are gene therapies that do not involve editing DNA

Breakthrough: Scientists attempt gene editing inside the human body, for the first timeScientists have tried editing a gene inside the body for the first time, in a bold attempt to tackle an incurable a disease by permanently changing a patient’s DNA. On Monday in California, Brian Madeux, a 44-year-old intravenously received billions of copies of a corrective gene and a genetic tool to cut his DNA in a […]

Explained: What is antibiotic resistance?

The World Health Organization (WHO) calls antibiotic resistance ‘one of the biggest threats to global health, food security, and development today’

Explained: What is antibiotic resistance?Bacteria are an integral part of our ecosystem and we share our bodies with many of these tiny creatures. However, they can be the root of serious health problems. There are roughly as many human cells as bacterial cells in our bodies, and our microscopic passengers pay their way by helping our immune system and […]

In a first, human gene edited to stop disease

Science is going through a golden age in editing DNA, thanks to a new technology called Crispr; named breakthrough of the year in just 2015. By using this technique, it's possible to reduce the burden of this heritable disease on the family and eventually the human race. However, this is not about to become routine practice. There is a question on its safety, and that can be answered only by far more extensive research

In a first, human gene edited to stop diseaseScientists have, for the first time, successfully freed embryos of a piece of faulty DNA that causes deadly heart disease to run in families. It potentially opens the door to preventing 10,000 disorders that are passed down the generations. The US and South Korean team allowed the embryos to develop for five days before stopping […]

Mumbai doctor treats twins with rare single-gene disorder

Doctors say Sanfilippo syndrome occurs among six children in a million. They emphasised on the need to evaluate such patients in a holistic manner

Mumbai doctor treats twins with rare single-gene disorderWhen Rajesh and Kavita K’s twins Lalita and Prerna (all names changed) were born, they were ecstatic. The couple in early 30s looked forward to a happy family life and raise their daughters to the best of their capacity. However, life had different plans for Rajesh and Kavita. They soon found themselves visiting doctors, trying […]

New study finds 12 genetic variants that raise ovarian cancer risk

The researchers located 12 new genetic variants associated with EOC risk. Additionally, the new study confirmed 18 previously identified variants that had been linked to the risk of developing EOC

New study finds 12 genetic variants that raise ovarian cancer riskOvarian cancer is a common form of cancer and a leading cause of cancer death among women. The genes we inherit affect our chances of developing ovarian cancer, and a new genomic study identifies 12 genetic variants associated with the risk. The Centers for Disease Control and Prevention (CDC) report that almost 21,000 women in […]

Gene mutation in women may be linked to unexplained infertility

Researchers find that women with mutations that lead to loss-of-function of some of the genes of NLRP family can fail to reproduce for reasons that may include recurrent loss of pregnancies with abnormally developing placentas, loss of embryo before implantation, or having a baby with developmental disabilities

Gene mutation in women may be linked to unexplained infertilityResearchers at Baylor College of Medicine, Texas Children’s Hospital and Rice University have uncovered a gene mutation that may provide answers to unexplained female infertility. The study appears in Scientific Reports, a member of the Nature family of journals. “Experts cannot identify the cause of the problem in an estimated 10 to 15 percent of […]

Gene that regulates bone growth can also help in cognition

Brain development in humans and other primates is profoundly affected by sensory experience and social interactions. Scientists have long sought to unravel genes in the brain that are turned on and off by experiences to fuel the rise of brain functions unique to such complex species

Gene that regulates bone growth can also help in cognitionA gene that regulates bone growth and muscle metabolism in mammals may take on an additional role as a promoter of brain maturation, cognition and learning in human and non-human primates, according to a new study led by neurobiologists at Harvard Medical School. Describing their findings in the Nov. 10 issue of Nature, researchers say […]