“We have been able to show that two known drugs lead to more profound effects on cancer cell proliferation than each drug alone,” said study first author Don Benjamin from the University of Basel in Switzerland.
“Data from this study support development of combination approaches for treatment of cancer patients,” Benjamin noted.
At higher doses, anti-diabetic drug inhibits growth of cancer cells, but could also induce unwanted side effects.
Study showed that cocktail of these two drugs is effective in a wide range of cancers.
“For example, in samples from leukaemia patients, we demonstrated that almost all tumour cells were killed by this cocktail and at doses that are actually not toxic to normal cells,” Benjamin said.
“And effect was exclusively confined to cancer cells, as blood cells from healthy donors were insensitive to treatment,” Benjamin noted.
Researchers found that drugs interrupt vital processes which provide energy for cancer cell.
Source: Times of India